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| 03:30 Club Blooming – Nacional Potosi : | | |
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| 04:00 Dallas – Minnesota United : | | |
| 04:00 Houston Dynamo – San Diego : | | |
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| 04:30 Atlas Guadalajara – Tigres de la UANL : | | |
| 04:30 Atletico San Luis – Santos Laguna : | | |
| 04:30 Mazatlan – Deportivo Toluca : | | |
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| 05:00 Club Universitario de Deportes – Deportivo Garcilaso : | | |
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| 05:00 Real Salt Lake – Inter Miami : | | |
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| 05:30 Oakland Roots – Las Vegas Lights : | | |
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| 06:00 Los Angeles – Colorado Rapids : | | |
| 06:00 San Jose Earthquakes – Austin : | | |
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| 06:30 Club Necaxa – Guadalajara : | | |
| 06:30 Tijuana – Pachuca : | | |
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| 16:00 Zorya Luhansk – Shakhtar Donetsk : | | |
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| 17:30 Radnicki Nis – Javor Ivanjica : | | |
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| 18:00 Akron Tolyatti – Dynamo Makhachkala : | | |
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| 18:30 AaB Fodbold – B.93 Copenhagen : | | |
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| 19:30 Nordsjaelland – AGF Aarhus : | | |
| 19:30 Randers – Fredericia : | | |
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| 19:30 Napredak Krusevac – IMT Novi Beograd : | | |
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| 19:40 Al-Najma Unaizah – Al-Taawon : | | |
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| 20:15 Go Ahead Eagles – AZ Alkmaar : | | |
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| 20:15 Akhmat – Baltika Kaliningrad : | | |
| 20:15 Spartak Moscow – Krasnodar : | | |
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| 20:30 AaB Fodbold – B.93 Copenhagen : | | |
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| 20:30 Levante UD – Sevilla : | | |
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| 20:30 Malmo – Sirius : | | |
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| 21:30 SonderjyskE – Midtjylland : | | |
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| 21:30 Zamalek – Pyramids : | | |
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| 21:30 Damac – Al-Okhdood : | | |
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| 21:30 Spartak Subotica – TSC Backa Topola : | | |
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| 21:30 Rayo Vallecano – Espanyol : | | |
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| 22:00 Sint-Truidense – Anderlecht : | | |
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| 22:30 San Antonio Bulo Bulo – Real Oruro : | | |
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| 22:30 Salford City – Bromley : | | |
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| 22:30 PSV Eindhoven – PEC Zwolle : | | |
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| 22:45 Valur – Hafnarfjordur : | | |
| 22:45 Vikingur Reykjavik – Stjarnan : | | |
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| 22:45 Casa Pia – Braga : | | |
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| 23:00 Real Oviedo – Villarreal : | | |
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| 23:30 Deportivo Los Chankas – Club Cienciano Cusco : | | |
